5 SIBO root causes you need to know for the recovery journey
You need to know about the common SIBO root causes if you constantly battle bloating, constipation or diarrhea, low energy, and more. For many, the list of symptoms continues, and the frustration grows with the uncertainty of what to eat and how to live a normal life.
These symptoms define the everyday life of those suffering from SIBO (Small Intestinal Bacterial Overgrowth).
However, many people who experience SIBO relapse soon realize that treatment itself may not be enough to get rid of the uncomfortable symptoms.
One important thing to understand about SIBO: SIBO is not an infection!
Certain factors allowed the bacteria to overgrow; identifying these SIBO root causes is critical to healing.
Often, people think it's only one thing that is causing their issues, but typically, several contributing factors are at play. It's crucial to stop just chasing the symptoms and start identifying the root causes of imbalance. Otherwise, we would just be mopping the floor instead of turning off the sink.
What is SIBO?
SIBO, or Small Intestinal Bacterial Overgrowth, is a condition where an excessive amount or abnormal type of bacteria are present in the small intestine, where their numbers should be relatively low compared to the large intestine. (The large intestine houses the highest number of bacteria). These bacteria in the wrong place can interfere with normal digestion and absorption of food by fermenting carbohydrates and fibers and creating byproducts, like gases (methane, hydrogen, hydrogen sulfide). The overgrown bacteria can interfere with normal digestion and nutrient absorption.
This process can lead to symptoms like:
- Chronic bloating that tends to get worse by the end of the day,
- Changed bowel movements involving constipation and/or diarrhea or alternating bowel movements
- Abdominal pain,
- Nausea,
- Burping,
- Fatigue,
- Muscle or joint pain,
- Mood changes,
- Brain fog, poor memory,
but it can also impact your skin, hormones, and other areas of the body. (1)
The SIBO root causes
Understanding the SIBO root causes is crucial in its effective management. SIBO is a complex condition, and its root causes can differ from person to person. This complexity is reflected in the research on complex diseases, which suggests that a multitude of factors may contribute to the onset of such conditions.
SIBO Root Cause #1: the role of gut motility
One of the key root causes of SIBO is issues with gut motility. The movement of the digestive system is crucial in maintaining a healthy balance of bacteria in the gut. When this movement is disrupted, it can lead to an overgrowth of bacteria in the small intestine.
This cause revolves around the role of the Migrating Motor Complex (MMC). The MMC is a pattern of electrical activity that occurs in the smooth muscle of the gastrointestinal tract during the periods between meals. It's often referred to as the "housekeeper" of our gut because its function is to sweep residual undigested material through the digestive tract. The MMC operates cyclically, approximately every 90-120 minutes during fasting periods.
When the MMC is functioning correctly, it helps control the bacterial population in the small intestine by regularly clearing it out, pushing bacteria into the large intestine, and preventing any significant accumulation. However, certain conditions like stress, medications (especially opioids), certain diseases (like Scleroderma), or other underlying causes can disrupt the MMC's functioning, leading to a slowdown or stoppage of this cleaning wave. This disruption can allow bacteria to multiply excessively in the small intestine, leading to SIBO. (2)
SIBO Root Cause #2: the impact of medications
Certain medications, such as proton pump inhibitors (PPIs), often prescribed for conditions like GERD (Gastroesophageal Reflux Disease), ulcers, and other acid-related disorders, reduce stomach acid production. While these medications provide relief from acid reflux symptoms, the reduced acid levels can have unintended consequences. Stomach acid is one of your body's primary defenses against bacterial overgrowth in the upper gut. When its production is inhibited by PPIs, the risk of bacterial overgrowth increases. Furthermore, with decreased stomach acidity, the body might not efficiently break down and absorb nutrients, potentially leading to nutrient deficiencies. Regular and prolonged use of PPIs has been linked to an increased risk of SIBO, emphasizing the importance of using these medications judiciously and under proper medical guidance. (3)(4)(5)
SIBO Root Cause #3: structural abnormalities in the gut
The physical structure of your gastrointestinal system can significantly influence the growth and movement of bacteria.
Here's how:
- Small Intestine Diverticula: These are small, bulging pouches that can form in the lining of the digestive system, primarily in the small intestine. These pouches can collect food particles and slow down transit time, allowing bacteria to grow and potentially leading to SIBO.
- Post-surgical Changes: Surgeries, especially those related to the digestive tract, like gastrectomies or bowel resections, can change the anatomy and movement of the gut. Such changes can create areas where food and bacteria stagnate, leading to bacterial overgrowth.
- Adhesions are bands of scar tissue that can form between abdominal tissues and organs, typically after surgery (C-section, endometriosis surgery). Adhesions can cause parts of the intestines to stick together, leading to blockages or slow transit times, promoting SIBO.
Other types of obstructions in the gut can also increase the risk of developing SIBO. (6)
SIBO Root Cause #4: reduced digestive juice production
Your body produces various digestive juices, from stomach acid to bile and digestive enzymes. These juices help break down food and also play a role in keeping bacterial growth in check. Factors like aging, certain medications, or other conditions can reduce the production of these juices, facilitating bacterial overgrowth. (7)
SIBO Root Cause #5: poor lifestyle choices
Your daily routines, habits, and choices are pivotal to your health. The gut, often called your "second brain," is no exception. Poor lifestyle choices alone may not directly cause SIBO, but they can contribute to the development of this condition.
Here's how your lifestyle can impact the gut:
- Dietary choices: the food you consume has an immediate effect on your gut health. Diets high in sugar, processed foods, and unhealthy fats can feed harmful bacteria, promoting their growth.
- Chronic stress affects your body in numerous ways; the gut is no exception. Persistent stress can weaken your gut lining, reduce stomach acid production, and alter gut motility, creating an environment for SIBO to flourish.
- Lack of physical activity: Sedentary lifestyles can slow down gut motility, creating an environment where bacteria can overgrow. On the other hand, regular (moderate) physical activity can boost metabolism and encourage healthy bowel movements.
- Alcohol consumption: Excessive alcohol intake can damage the gut lining and disrupt the balance of beneficial bacteria. It can also decrease stomach acid production, making the small intestine more susceptible to bacterial overgrowth.
- Inadequate sleep: Your body needs adequate rest for repair and regeneration. Consistently missing out on restful sleep can weaken the immune system, making your body and gut more vulnerable to imbalances and infections.
Your path to recovery
If you suspect you have SIBO, requesting a SIBO breath test to get a diagnosis is crucial. You may need a tailored treatment plan based on the breath test result. Given the individual-specific nature of SIBO's root causes, it's vital to approach treatment on a case-by-case basis. Recovery often involves a combination of dietary changes, antibiotics or natural antimicrobials, and possibly prokinetic drugs to improve gut motility while addressing any root causes.
SIBO, while challenging, is manageable. With the right knowledge and tools at your disposal, recovery is not just possible – it's probable. Take the first step towards your gut health transformation and join the SIBO Root Cause Masterclass today. We will break down the five most common root causes of SIBO, going beyond the surface to understand the underlying mechanisms and how they affect your gut health. Armed with the knowledge of the root causes, the next step is a solution-oriented approach. The masterclass offers practical, actionable strategies tailored to each cause, ensuring you have a toolkit to combat SIBO. By deeply understanding the common root causes of SIBO, you're better equipped to prevent and manage this condition.
This post is only for informational purposes and is not meant to diagnose, treat, or cure any disease. I recommend always consulting your healthcare practitioner before trying any treatment or dietary changes.
- Achufusi, T. G. O., Sharma, A., Zamora, E. A., & Manocha, D. (2020). Small Intestinal Bacterial Overgrowth: Comprehensive Review of Diagnosis, Prevention, and Treatment Methods. Cureus, 12(6), e8860. https://doi.org/10.7759/cureus.8860
- Deloose, E., Janssen, P., Depoortere, I., & Tack, J. (2012). The migrating motor complex: control mechanisms and its role in health and disease. Nature reviews. Gastroenterology & hepatology, 9(5), 271–285. https://doi.org/10.1038/nrgastro.2012.57
- Lo, W. K., & Chan, W. W. (2013). Proton pump inhibitor use and the risk of small intestinal bacterial overgrowth: a meta-analysis. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 11(5), 483–490. https://doi.org/10.1016/j.cgh.2012.12.011
- Fujimori S. (2015). What are the effects of proton pump inhibitors on the small intestine?. World journal of gastroenterology, 21(22), 6817–6819. https://doi.org/10.3748/wjg.v21.i22.6817
- Lombardo, L., Foti, M., Ruggia, O., & Chiecchio, A. (2010). Increased incidence of small intestinal bacterial overgrowth during proton pump inhibitor therapy. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 8(6), 504–508. https://doi.org/10.1016/j.cgh.2009.12.022
- Dukowicz, A. C., Lacy, B. E., & Levine, G. M. (2007). Small intestinal bacterial overgrowth: a comprehensive review. Gastroenterology & hepatology, 3(2), 112–122.
- Bures, J., Cyrany, J., Kohoutova, D., Förstl, M., Rejchrt, S., Kvetina, J., Vorisek, V., & Kopacova, M. (2010). Small intestinal bacterial overgrowth syndrome. World journal of gastroenterology, 16(24), 2978–2990. https://doi.org/10.3748/wjg.v16.i24.2978
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